Pioneering multi-functional small molecules to combat neurodegenerative diseases
Innovative chemistry platform to generate first-in-class small molecules modulating three known processes involved in neurodegeneration: protein misfolding, oxidative stress and neuro-inflammation
Our Trojan horse
Ilios is the ancient name of Troy. Our Trojan horse delivers multi-functional drugs to the brain.
Multi-functional
small molecules
Modulating three known disease processes: protein mislocalization, oxidative stress and neuroinflammation
Rational-design merges validated components
Merging bioactive pharmacophores with glutathione and fatty acids to create brain-penetrant compounds that overcome limitations of individual components
Chemistry platform builds pipeline
Innovative chemistry platform to address multiple neurodegenerative diseases
Novel approach
A first in class multi-functional molecule to combat neurodegeneration
Rationally designing multi-functional molecule
Lead program in ALS
Pathophysiology-specific functional screens
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TDP-43 mislocalization
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Disregulated NRF-2
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Inflamed microglia
Platform leverages bioactive pharmacophores to build pipeline
Seeking collaborations to accelerate and expand our pipeline