
Trojan Horse Platform against Neurodegenerative Diseases
Disease-modifying first in class small molecules targeting multiple complementary mechanisms upstream neurodegenerative signaling cascade
What We Do
Multi-targeted Small Molecules
Targeting multiple pathways to counter brain inflammation, oxidative stress, and the aggregation of selected proteins
Flexible
Platform
Versatile platform optimized to target diverse diseases including ALS, Frontotemporal Dementia, Traumatic Brain Injury, Parkinson's, and Alzheimer's
Novel Chemistry, Validated Agents
First generation
New Chemical Entities (NCEs) brings together therapeutic agents subjects of decades of research by our Academic
Co-founders.
Intelligent Drug Discovery
Next generation NCEs drug discovery utilizes a machine learning trained model to screen through the millions of permutations that our platform allows
Innovative approach to neurodegeneration
Target multiple complementary mechanisms with a single drug.
First in class NCEs optimized to target multiple pathways upstream neurodegenerative cascade: misfolded protein disaggregation, brain inflammation and oxidative stress.

Our Trojan Horse
Synergistic activity in rationally designed single NCEs combining validated naturally occurring ligands
Our patent pending technology harnesses the full potential of Glutathione as a therapeutic linker. Synthesized with Fatty Acids and other Payloads, our NCEs synergistically target multiple pathways

Flexible platform
We optimize candidates targeting different pathways: data driven indication strategy


"Ilios is the ancient name of Troy.
We are bringing to life a Trojan Horse for the brain to provide an innovative alternative to complex drug discovery by bringing together three components validated on known biological pathways of neurodegenerative diseases."
Luca Giani, Co-founder and CEO, Ilios Tx
Get in Touch
Let's make neurodegenerative diseases a thing of the past, together.
Pagliuca Harvard Life Labs
127 Western Avenue, Allston, MA 02134
MassChallenge - Boston Seaport Office
10 Fan Pier Boulevard 3rd floor, Boston, MA 02210
+1 (760) 301-6426